منابع مشابه
Supergenes and Complex Phenotypes
Understanding the molecular underpinnings of evolutionary adaptations is a central focus of modern evolutionary biology. Recent studies have uncovered a panoply of complex phenotypes, including locally adapted ecotypes and cryptic morphs, divergent social behaviours in birds and insects, as well as alternative metabolic pathways in plants and fungi, that are regulated by clusters of tightly lin...
متن کاملSupergenes: The Genomic Architecture of a Bird with Four Sexes
Supergenes are clusters of physically linked, co-evolving genes that often control complex traits. A new study clarifies the origin and possible fate of a fascinating supergene that determines the coloration and mating behavior of a widespread North American bird.
متن کاملSocial dilemmas among supergenes: intragenomic sexual conflict and a selfing solution in Oenothera.
Recombination is a powerful policing mechanism to control intragenomic cheats. The "parliament of the genes" can often rapidly block driving genes from cheating during meiosis. But what if the genome parliament is reduced to only two members, or supergenes? Using a series of simple game-theoretic models inspired by the peculiar genetics of Oenothera sp., we illustrate that a two supergene genom...
متن کاملThe status of supergenes in the 21st century: recombination suppression in Batesian mimicry and sex chromosomes and other complex adaptations
I review theoretical models for the evolution of supergenes in the cases of Batesian mimicry in butterflies, distylous plants and sex chromosomes. For each of these systems, I outline the genetic evidence that led to the proposal that they involve multiple genes that interact during 'complex adaptations', and at which the mutations involved are not unconditionally advantageous, but show advanta...
متن کاملBiological Knowledge Integration in DNA Microarray Gene Expression Classification Based on Rough Set Theory
DNA microarrays have contributed to the exponential growth of genetic data from years. This large amount of gene expression data have been used in researches seeking diagnosis of diseases like cancer using classification methods. In turn, explicit biological knowledge about gene functions has also grown tremendously over the last decade. This work integrates explicit biological knowledge in cla...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2019
ISSN: 0960-9822
DOI: 10.1016/j.cub.2019.05.024